Journal: Scientific Reports

Article Title: Positive impact of Platelet-rich plasma and Platelet-rich fibrin on viability, migration and proliferation of osteoblasts and fibroblasts treated with zoledronic acid

doi: 10.1038/s41598-019-43798-z

Figure Lengend Snippet: Preinvestigation of PRP and PRF for in-vitro addition. The effect of PRP and PRF were examined in different concentrations to fibroblasts ( A ) and osteoblasts ( B ) by real- time cell analysis.

Article Snippet: The fibroblast and osteoblast growth medium (FGM and OGM; both from Provitro®; Berlin Germany) were each supplemented with 10% fetal bovine serum (FBS, Provitro® GmbH) and 1% antibiotics (100 U/ml penicillin G, 100 μg/ml streptomycin).

Techniques: In Vitro, Cell Analysis

Journal: Scientific Reports

Article Title: Positive impact of Platelet-rich plasma and Platelet-rich fibrin on viability, migration and proliferation of osteoblasts and fibroblasts treated with zoledronic acid

doi: 10.1038/s41598-019-43798-z

Figure Lengend Snippet: Representative photographs of cell migration using the scratch assay. The effect of ZA, PRP, PRF and their combination on the migration of fibroblasts ( A ) and osteoblasts ( B ) were examined (PC = positive control; NC = negative control; ZA = zoledronic acid).

Article Snippet: The fibroblast and osteoblast growth medium (FGM and OGM; both from Provitro®; Berlin Germany) were each supplemented with 10% fetal bovine serum (FBS, Provitro® GmbH) and 1% antibiotics (100 U/ml penicillin G, 100 μg/ml streptomycin).

Techniques: Migration, Wound Healing Assay, Positive Control, Negative Control

Journal: Scientific Reports

Article Title: Positive impact of Platelet-rich plasma and Platelet-rich fibrin on viability, migration and proliferation of osteoblasts and fibroblasts treated with zoledronic acid

doi: 10.1038/s41598-019-43798-z

Figure Lengend Snippet: Percentage of closure of the scratch area in fibroblasts ( A ) and osteoblasts ( B ) in the different groups (1.0 = 100% coverage). Significant difference ( p < 0.05) is marked with *.

Article Snippet: The fibroblast and osteoblast growth medium (FGM and OGM; both from Provitro®; Berlin Germany) were each supplemented with 10% fetal bovine serum (FBS, Provitro® GmbH) and 1% antibiotics (100 U/ml penicillin G, 100 μg/ml streptomycin).

Techniques:

Journal: Scientific Reports

Article Title: Positive impact of Platelet-rich plasma and Platelet-rich fibrin on viability, migration and proliferation of osteoblasts and fibroblasts treated with zoledronic acid

doi: 10.1038/s41598-019-43798-z

Figure Lengend Snippet: Effects of PRP, PRF, ZA and their combinations on the viability of human gingival fibroblasts ( A ) and osteoblasts ( B ) assessed by MTT assay. Significant difference ( p < 0.05) is marked with *.

Article Snippet: The fibroblast and osteoblast growth medium (FGM and OGM; both from Provitro®; Berlin Germany) were each supplemented with 10% fetal bovine serum (FBS, Provitro® GmbH) and 1% antibiotics (100 U/ml penicillin G, 100 μg/ml streptomycin).

Techniques: MTT Assay

Journal: Scientific Reports

Article Title: Positive impact of Platelet-rich plasma and Platelet-rich fibrin on viability, migration and proliferation of osteoblasts and fibroblasts treated with zoledronic acid

doi: 10.1038/s41598-019-43798-z

Figure Lengend Snippet: Cell proliferation assessed by real-time cell analysis for fibroblasts ( A ) and osteoblasts ( B ) in the different groups over a period of 72 h. The values are the median of the measured cell index. Significant difference ( p < 0.05) is marked with *.

Article Snippet: The fibroblast and osteoblast growth medium (FGM and OGM; both from Provitro®; Berlin Germany) were each supplemented with 10% fetal bovine serum (FBS, Provitro® GmbH) and 1% antibiotics (100 U/ml penicillin G, 100 μg/ml streptomycin).

Techniques: Cell Analysis